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生物通
9月
IL-33:肺癌 DNA 损伤抗性的关键 “推手” 与潜在治疗靶点
为探究肿瘤微环境(TME)中白细胞介素 - 33(IL-33)在肺癌治疗抵抗中的作用机制,研究人员开展了相关研究。结果发现 IL-33 可通过激活 MAPK/NHEJ 通路,促进肿瘤细胞 DNA 损伤修复,增强肺癌对化疗药物的抗性。该研究为肺癌治疗提供了新方向。 在肿瘤治疗的战场 ...
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